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Selenium in biology : ウィキペディア英語版 | Selenium in biology
Although it is toxic in large doses, selenium is an essential micronutrient for animals. In plants, it sometimes occurs in amounts toxic as forage, e.g. locoweed. Selenium is a component of the amino acids selenocysteine and selenomethionine. In humans, selenium is a trace element nutrient that functions as cofactor for glutathione peroxidases and certain forms of thioredoxin reductase.〔S. J. Lippard, J. M. Berg "Principles of Bioinorganic Chemistry" University Science Books: Mill Valley, CA; 1994. ISBN 0-935702-73-3.〕 Selenium-containing proteins are produced from inorganic selenium via the intermediacy of selenophosphate (PSeO33−). ==Se-containing biomolecules==
Selenium is an essential micronutrient in mammals, but is also recognized as toxic in excess. Selenium exerts its biological functions through selenoproteins, which contain the amino acid selenocysteine. Twenty-five selenoproteins are encoded in the human genome.
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